The search for infectious causes of human cancers: where and why (Nobel lecture).
نویسنده
چکیده
Slightly more than 20% of the global cancer burden can currently be linked to infectious agents, including viruses, bacteria, and parasites. In this Review the reasons for their relatively late discovery are analyzed, and epidemiological observations that may point to an involvement of additional infectious agents in specific human cancers are highlighted. Emphasis is placed on hematopoietic malignancies, breast and colorectal cancers, as well as basal cell carcinomas of the skin and lung cancers in nonsmokers.
منابع مشابه
Casual role of infectious agents in cancer: An overview
Cancer is a complex group of diseases with multiple eventual causes. The underlying causes are not fully known. Thus, learning more about the known causes of cancer is an important issue. Moreover, among these factors, infection and its association to cancers is controversial. Although, it seems that the genome instability of the cells can initiate cancer development. The purpose of this review...
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Slightly more than 20% of the global cancer burden can currently be linked to infectious agents, including viruses, bacteria and parasites. This manuscript analyses reasons for their relatively late discovery and highlights epidemiological observations that may point to the involvement of additional infectious agents in specific human cancers. Emphasis is placed on haematopoietic malignancies, ...
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عنوان ژورنال:
- Angewandte Chemie
دوره 48 32 شماره
صفحات -
تاریخ انتشار 2009